What causes retroperitoneal fibrosis?

Risk factors for retroperitoneal fibrosis include asbestos exposure, smoking, tumor , infection, trauma, radiotherapy, surgery, and use of certain drugs. Treatment may include corticosteroids , tamoxifen, stents or surgery.

What is IgG4 disease and the causes?

The cause of IgG4-RD is unknown, but is thought to involve autoimmunity because of its chronic, insidious nature, the targeting of self-proteins by antibodies (1 Etiology reference Immunoglobulin G4-related disease (IgG4-RD) is a chronic immune-mediated fibroinflammatory disorder that often manifests with tumor-like …

Is retroperitoneal fibrosis an autoimmune disease?

Retroperitoneal fibrosis is a rare autoimmune related disorder that blocks the tubes (ureters) that carry urine from the kidneys to the bladder. Retroperitoneal fibrosis is a rare autoimmune related disorder that blocks the tubes (ureters) that carry urine from the kidneys to the bladder.

Can retroperitoneal fibrosis go away on its own?

In some cases, physicians may wrap a layer of fat around the ureter in an attempt to prevent the recurrence of ureter obstruction. In some reported cases, retroperitoneal fibrosis has subsided on its own without treatment (spontaneous resolution).

What drugs can cause retroperitoneal fibrosis?

Cause of retroperitoneal fibrosis

  • prescription drugs, including certain beta-blockers (used to treat heart and blood pressure conditions) and an ergot derivative used in the past for migraine.
  • illegal drugs, including cocaine.
  • abdominal aortic aneurysm (abnormal swelling of the aorta)
  • urinary tract injury.
  • infection.

Can retroperitoneal fibrosis be cancerous?

Retroperitoneal fibrosis (RPF) is the abnormal growth of white and ‘woody’ tissue on and around the structures of the abdomen that are outside the peritoneum. Occasionally, the tissue can be cancerous. RPF is also known as Ormond’s disease.

What is IgG4 related disease?

Jump to navigation Jump to search. IgG4-related disease (IgG4-RD), formerly known as IgG4-related systemic disease, is a chronic inflammatory condition characterized by tissue infiltration with lymphocytes and IgG4-secreting plasma cells, various degrees of fibrosis (scarring) and a usually prompt response to oral steroids.

What is retroperitoneal pain?

“Retroperitoneal” refers to the back of the peritoneum, the membrane that lines the anatomical space in the abdominal cavity. Kidney stones may cause pain to the organs within the retroperitoneal space.

What is peritoneal fibrosis?

Peritoneal Fibrosis. Disorder characterized by a wide range of structural changes in PERITONEUM, resulting from fibrogenic or inflammatory processes. Peritoneal fibrosis is a common complication in patients receiving PERITONEAL DIALYSIS and contributes to its gradual decrease in efficiency.