What are the complications of blood transfusion?

Some of the most common complications in blood transfusions are listed below.

  • Allergic Reactions. Some people have allergic reactions to blood received during a transfusion, even when given the right blood type.
  • Fever. Developing a fever after a transfusion is not serious.
  • Acute Immune Hemolytic Reaction.

What are the complications of exchange transfusions in the newborn?

Frequency of Exchange Transfusion During and immediately after exchange transfusion, 57 (38.5%) neonates developed complications. Most complications were thrombocytopenia (17.6%), hypocalcemia (11.5%), hypoglycemia (9.5%), hyperkalemia (5.4%), hyponatremia (4.1%), apnea (4.7%), and septicemia (2%).

Which of the following are risks that could be associated to neonate transfusion?

Metabolic complications Hypoglycemia, hyperkalemia, and hypocalcemia are the most common metabolic complications associated with transfusion in neonates.

What is the most serious complication of blood transfusion?

Haemolytic transfusion reactions The most serious complications of blood transfusion result from interactions between antibodies in the recipient’s plasma and surface antigens on donor RBCs.

Do blood transfusions weaken immune system?

Transfused blood also has a suppressive effect on the immune system, which increases the risk of infections, including pneumonia and sepsis, he says. Frank also cites a study showing a 42 percent increased risk of cancer recurrence in patients having cancer surgery who received transfusions.

What are the complications of phototherapy?

Side effects — Phototherapy is very safe, but it can have temporary side effects, including skin rashes and loose stools. Overheating and dehydration can occur if a baby does not get enough breast milk or formula.

When do newborns need transfusion?

The indications for neonatal RBC transfusions differ based upon the rate of fall in hemoglobin (acute versus chronic anemia). The need for transfusion in an infant with acute blood loss is generally dependent upon persistent clinical signs of inadequate oxygen delivery following intravascular volume restoration.

What is TRALI transfusion reaction?

TRALI is an acute complication following blood transfusion that is characterized by severe shortness of breath, often associated with fever and low blood pressure. Although rare, it is one of the most common causes of transfusion- related death.

How many children have complications from blood transfusions?

Of those patients who received transfusions, 492 (0.95%) experienced a complication from the administered blood product. This accounted for a rate of complications of 10.7 per 1,000 units transfused. Conclusions: The administration of blood products to children is a common practice in academic children’s hospitals.

Can a neonatologist do a blood transfusion?

Many previously widely accepted neonatal transfusion practices are changing as neonatologists become more aware of the risks to their patients of multiple blood product transfusions.

Is it safe to do exchange transfusion in neonates?

Although the frequency of neonatal exchange transfusion has declined markedly in the past two decades, this procedure is still performed in many countries, especially in those with a high incidence of neonatal hyperbilirubinemia. Exchange transfusion is effective and considered to be safe procedure ; however, it is not without risks.

When to use RBC transfusion in neonatal care?

In modern neonatal care, this is increasingly the case in the era of antenatal steroids, surfactant, limited acute lung disease, nasal continuous positive airways pressure, and low oxygen requirement. Taking into consideration the available evidence, we use the following RBC transfusion practice in neonates.